SCHEMBL6960132

SCHEMBL6960132

CC(=S)NC[C@@H]1CN(c2ccc3c(c2)OC[C@@H](C)N3C(=O)O)C(=O)O1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.52
MAOB P27338 5/20 0.52
PTGS1 P23219 2/20 0.52
SDHA P31040 2/20 0.52
LMNA P02545 1/20 0.52
CALML3 P27482 1/20 0.52
F10 P00742 9/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6960123 1.00 MAOA (0.52) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6968031 0.94 MAOA (0.57) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6964604 0.86 MAOA (0.50) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6971579 0.86 MAOA (0.50) MAOAMAOBPTGS1SDHALMNA
SCHEMBL7533913 0.86 MAOA (0.50) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6040490 0.85 MAOB (0.48) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6974618 0.84 MAOA (0.50) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6974624 0.84 MAOA (0.50) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6967768 0.82 MAOA (0.49) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6040303 0.81 MAOA (0.55) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181288-B1 BICYCLIC OXAZOLIDINONES AS ANTIBACTERIAL AGENT UPJOHN CO (US) 2003-07-30 EP disclosed
US-20020143009-A1 Novel bicyclic oxazolidinones as antibacterial agents PHARMACIA & UPJOHN 2002-10-03 US disclosed
US-6387896-B1 GRAMNEGATIVE, GRAMPOSITVE BACTERIA PHARMACIA & UPJOHN CO. 2002-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020143009-A1 Novel bicyclic oxazolidinones as antibacterial agents OXA1L, MRPL21, RPS4Y1 MAOA 1716/4885MAOB 1600/4885PTGS1 1189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.