Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.47 |
| ▸ | DRD3 | P35462 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960377 | 0.85 | HRH1 (0.50) | HRH1DRD3HTR1AHTR2AADRA1D | |
| Hydrochloric Acid SCHEMBL6960160 | 0.84 | HRH1 (0.49) | HRH1DRD3HTR1AHTR2AADRA1D | |
| SCHEMBL6962085 | 0.80 | HRH1 (0.46) | HRH1DRD3HTR1AHTR2AADRA1D | |
| SCHEMBL6965352 | 0.78 | DRD3 (0.58) | DRD3HTR1AHTR2AADRA1DADRA1A | |
| SCHEMBL6973725 | 0.78 | HRH1 (0.47) | HRH1DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL6970843 | 0.77 | DRD3 (0.58) | DRD3HTR1AHTR2AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL6969843 | 0.76 | DRD3 (0.57) | DRD3HTR1AHTR2AADRA1DADRA1A | |
| SCHEMBL6960861 | 0.74 | HRH1 (0.53) | HRH1DRD3HTR1AADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL6960646 | 0.73 | HRH1 (0.52) | HRH1DRD3HTR1AADRA1DADRA1A | |
| SCHEMBL6963499 | 0.72 | HRH1 (0.49) | HRH1DRD3ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |