Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 9/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960765 | 0.89 | HRH1 (0.42) | HRH1SIGMAR1HTR1ADRD3HRH3 | |
| SCHEMBL6964899 | 0.86 | HRH1 (0.40) | HRH1SIGMAR1HTR1ADRD2ADRA1D | |
| SCHEMBL6963499 | 0.85 | HRH1 (0.49) | HRH1DRD3HRH3DRD1ADRA1D | |
| Hydrochloric Acid SCHEMBL6970215 | 0.84 | HRH1 (0.49) | HRH1DRD3HRH3DRD1ADRA1D | |
| SCHEMBL6963659 | 0.80 | HRH1 (0.45) | HRH1DRD3HRH3DRD2DRD1 | |
| SCHEMBL6970693 | 0.79 | CCR1 (0.41) | HRH1HTR1ADRD3DRD2ADRA1D | |
| SCHEMBL6965928 | 0.78 | DRD2 (0.59) | DRD3DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL6965751 | 0.78 | HSD11B1 (0.55) | SIGMAR1 | |
| SCHEMBL6960633 | 0.78 | HRH1 (0.47) | HRH1SIGMAR1HTR1ADRD3HRH3 | |
| Hydrochloric Acid SCHEMBL6972143 | 0.78 | DRD2 (0.58) | DRD3DRD2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934312-B1 | 1,4-DISUBSTITUTED PIPERAZINES | NOVO NORDISK AS (DK) | 2003-03-19 | — | — | EP | claimed |