SCHEMBL6960668

SCHEMBL6960668

c1ccc(COCCCOc2ccc(C3C(CSc4ccccc4)CNCC3OCc3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.89

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6042608 0.99 REN (0.88) REN
SCHEMBL6044003 0.94 REN (1.00) REN
SCHEMBL6043539 0.94 REN (1.00) REN
Hydrochloric Acid SCHEMBL6043264 0.94 REN (0.98) REN
SCHEMBL6959506 0.89 REN (0.87) REN
SCHEMBL8347144 0.89 REN (0.87) REN
SCHEMBL6042763 0.88 REN (0.80) REN
SCHEMBL6042756 0.88 REN (0.80) REN
Hydrochloric Acid SCHEMBL6041600 0.88 REN (0.86) REN
Hydrochloric Acid SCHEMBL6041605 0.88 REN (0.86) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999012532-A2 PIPERIDINE DERIVATIVES AGAINST MALARIA F.HOFFMANN-LA ROCHE AG (CH) 1999-03-18 WO claimed
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed