Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17236166 | 0.83 | SMN1; SMN2 (0.77) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17336774 | 0.83 | KDM4E (0.64) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31305679 | 0.83 | KDM4E (0.64) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL401199 | 0.80 | L3MBTL1 (0.64) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15281674 | 0.80 | L3MBTL1 (0.59) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31325120 | 0.80 | L3MBTL1 (0.59) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL265872 | 0.80 | HDAC8 (0.69) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28062202 | 0.80 | L3MBTL1 (0.59) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4652925 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL17336679 | 0.78 | SMN1; SMN2 (0.64) | PARP1L3MBTL1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |