Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BIRC2 | Q13490 | 2/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165463 | 0.85 | BIRC2 (0.60) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL2208006 | 0.84 | NOTUM (0.78) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL27165447 | 0.83 | BIRC2 (0.57) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6962584 | 0.83 | BIRC2 (0.57) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL7984550 | 0.81 | NOTUM (0.60) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL30912010 | 0.81 | NOTUM (0.57) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL6970556 | 0.81 | XIAP (0.57) | NOTUMSMN1; SMN2RAB9AMAPTNPC1 | |
| SCHEMBL416024 | 0.81 | BIRC2 (0.55) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL26691241 | 0.80 | NOTUM (0.58) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT | |
| SCHEMBL30911987 | 0.80 | BIRC2 (0.54) | BIRC2NOTUMSMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807631-B1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO CO (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-5981752-A | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY, LIMITED (JP) | 1999-11-09 | — | — | US | disclosed |
| US-5773618-A | PYRROLOQUINOLINONE DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0807631-A1 | Tricyclic compounds having fungicidal activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-11-19 | — | — | EP | disclosed |