Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 11/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRK2 | P25098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514635 | 0.86 | AAK1 (0.47) | AAK1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL13514634 | 0.85 | AAK1 (0.47) | AAK1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL30746576 | 0.85 | LPAR1 (0.51) | AAK1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL2074231 | 0.85 | LPAR1 (0.51) | AAK1RAB9ANPC1LMNAMEN1 | |
| SCHEMBL17047591 | 0.83 | TSHR (0.52) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL12521472 | 0.82 | MAPK1 (0.48) | AAK1RAB9ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL23958628 | 0.82 | AAK1 (0.49) | AAK1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL30007095 | 0.82 | AAK1 (0.49) | AAK1RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL23143981 | 0.82 | CREBBP (0.47) | RAB9AKDM4EMITFNPC1THRB | |
| SCHEMBL29182716 | 0.81 | ALDH1A1 (0.56) | RAB9AKDM4EMITFNPC1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013151033-A1 | C-GLYCOSIDE DERIVATIVE HAVING A SPIRO RING | 第一三共株式会社 (JP) | 2013-10-10 | — | — | WO | disclosed |
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| EP-1362041-A1 | ARYL CARBAMATE DERIVATIVES, PREPARATION AND USE THEREOF | Cerep (FR) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002068399-A1 | ARYL CARBAMATE DERIVATIVES, PREPARATION AND USE THEREOF | CEREP (FR) | 2002-09-06 | — | — | WO | disclosed |