SCHEMBL6961020

SCHEMBL6961020

COCCN(CCOC)c1nc(Cl)nc(N(CCOC)CCOC)n1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 1/20 0.46
▸ CRHR1 P34998 7/20 0.41
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ DYRK1A Q13627 1/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.35
▸ LMNA P02545 3/20 0.35
▸ MAPT P10636 2/20 0.33
▸ CTH P32929 1/20 0.33
▸ CDC7 O00311 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ ALOX15 P16050 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2115019 0.89 SLC29A1 (0.53) SLC29A1CRHR1MEN1KMT2ADYRK1A
SCHEMBL8817087 0.78 ALDH1A1 (0.32) KMT2AALDH1A1ALOX15TSHR
SCHEMBL12994846 0.77 SLC29A1 (0.44) SLC29A1CRHR1MEN1KMT2ASMN1; SMN2
SCHEMBL31530718 0.76 MAPT (0.55) SLC29A1CRHR1MEN1KMT2ASMN1; SMN2
SCHEMBL523376 0.72 MAPT (0.42) SLC29A1CRHR1MEN1KMT2ASMN1; SMN2
SCHEMBL11735724 0.71 MAPT (0.50) SLC29A1CRHR1MEN1KMT2ASMN1; SMN2
SCHEMBL6966357 0.71 SLC29A1 (0.48) SLC29A1MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL1872550 0.70 TDP1 (0.52) SLC29A1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL28294136 0.70 TDP1 (0.52) SLC29A1KMT2ASMN1; SMN2LMNAMAPT
SCHEMBL13299491 0.69 MAPT (0.40) SLC29A1CRHR1KMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0782994-B1 Block oligomers containing 2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials CIBA SC HOLDING AG (CH) 2003-02-05 — — EP disclosed
US-6297299-B1 CONTAINING TRIAZINE GROUPS CIBA SPECIALTY CHEMICALS CORP. 2001-10-02 — — US disclosed
US-6046304-A MIXTURE OF SPECIFIC BLOCK OLIGOMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION WITH TRIAZINE AND 2,2,6,6-TETRAMETHYL-4-PIPERIDYL GROUPS; USE AS LIGHT STABILIZERS, HEAT STABILIZERS AND OXIDATION STABILIZERS SUCH AS FOR SYNTHETIC POLYMERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-04-04 — — US disclosed
EP-0782994-A1 Block oligomers containing 2,2,6,6-tetramethyl-4-piperidyl groups as stabilizers for organic materials Ciba SC Holding AG (CH) 1997-07-09 — — EP disclosed
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