Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9869942 | 0.89 | GAA (0.69) | GAASMN1; SMN2KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL5657811 | 0.88 | GAA (0.60) | GAASMN1; SMN2KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL6954631 | 0.86 | KMT2A (0.68) | SMN1; SMN2KMT2AL3MBTL1CYP2C19POLB | |
| SCHEMBL10895253 | 0.84 | GAA (0.71) | GAASMN1; SMN2KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL14027684 | 0.82 | TDP1 (0.67) | GAAL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL10457597 | 0.81 | NPC1 (0.65) | GAASMN1; SMN2KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL8110954 | 0.80 | GAA (0.75) | GAASMN1; SMN2KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL9297476 | 0.80 | KMT2A (0.75) | GAASMN1; SMN2KMT2AL3MBTL1CYP2C19 | |
| SCHEMBL14027686 | 0.80 | ALDH1A1 (0.54) | GAALMNAPOLBTDP1ALDH1A1 | |
| SCHEMBL17856292 | 0.80 | NPC1 (0.65) | SMN1; SMN2KMT2AL3MBTL1CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362041-A1 | ARYL CARBAMATE DERIVATIVES, PREPARATION AND USE THEREOF | Cerep (FR) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002068399-A1 | ARYL CARBAMATE DERIVATIVES, PREPARATION AND USE THEREOF | CEREP (FR) | 2002-09-06 | — | — | WO | disclosed |