Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | HTR1A | P08908 | 15/20 | 0.68 |
| ▸ | HTR1B | P28222 | 15/20 | 0.68 |
| ▸ | DRD4 | P21917 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966491 | 0.93 | HTR1A (0.69) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6953768 | 0.90 | KCNH2 (0.72) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6968255 | 0.89 | KCNH2 (0.73) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6966989 | 0.87 | KCNH2 (0.71) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6967386 | 0.87 | KCNH2 (0.71) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6957072 | 0.87 | KCNH2 (0.73) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6965636 | 0.87 | KCNH2 (0.72) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6961378 | 0.87 | KCNH2 (0.72) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6966424 | 0.86 | KCNH2 (0.74) | KCNH2HTR1AHTR1BDRD4DRD3 | |
| SCHEMBL6961741 | 0.86 | KCNH2 (0.77) | KCNH2HTR1AHTR1BDRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602889-B1 | 5-heteroaryl substituted indoles | H. LUNDBECK A.S. (DK) | 2003-08-05 | — | — | US | claimed |
| EP-1068198-B1 | 5-HETEROARYL SUBSTITUTED INDOLES | LUNDBECK & CO AS H (DK) | 2003-05-28 | — | — | EP | claimed |
| US-6602889-B1 | 5-heteroaryl substituted indoles | H. LUNDBECK A.S. (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-1068198-B1 | 5-HETEROARYL SUBSTITUTED INDOLES | LUNDBECK & CO AS H (DK) | 2003-05-28 | — | — | EP | disclosed |