Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963362 | 0.94 | KMT2A (0.34) | HIF1AKMT2ASMN1; SMN2NPSR1AURKA | |
| SCHEMBL6964427 | 0.94 | KMT2A (0.35) | HIF1AKMT2ASMN1; SMN2NPSR1MAPT | |
| SCHEMBL6957853 | 0.92 | KMT2A (0.34) | KMT2ASMN1; SMN2NPSR1MAPTKDM4C | |
| SCHEMBL6963254 | 0.92 | TP53 (0.33) | KMT2ASMN1; SMN2NPSR1MAPTTP53 | |
| SCHEMBL6956125 | 0.91 | KMT2A (0.35) | KMT2ASMN1; SMN2NPSR1MAPTTP53 | |
| SCHEMBL6958073 | 0.90 | KMT2A (0.33) | KMT2ASMN1; SMN2NPSR1MAPTKDM4C | |
| SCHEMBL6959003 | 0.90 | TP53 (0.41) | KMT2ASMN1; SMN2NPSR1MAPTTP53 | |
| SCHEMBL6965486 | 0.90 | KMT2A (0.37) | KMT2ASMN1; SMN2NPSR1MAPTTP53 | |
| SCHEMBL6962832 | 0.89 | NR1D1 (0.34) | KMT2ASMN1; SMN2NPSR1MAPTTP53 | |
| SCHEMBL6962863 | 0.89 | KMT2A (0.38) | KMT2ASMN1; SMN2NPSR1MAPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | claimed |
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6352993-B1 | ANTIULCER AGENTS | YUHAN CORPORATION (KR) | 2002-03-05 | — | — | US | disclosed |