SCHEMBL6961940

SCHEMBL6961940

c1c[nH]c(-c2nnco2)n1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
NOTUM Q6P988 12/20 0.39
NISCH Q9Y2I1 2/20 0.39
MTOR P42345 1/20 0.39
ADK P55263 1/20 0.39
TSHR P16473 1/20 0.34
ADRA2A P08913 1/20 0.34
KDM4E B2RXH2 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1285815 0.71 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ANISCHMTOR
SCHEMBL6961937 0.71 NISCH (0.38) ALDH1A1MEN1KMT2ANISCHMTOR
SCHEMBL12906161 0.69 NOTUM (0.59) ALDH1A1NOTUMTSHRKDM4E
SCHEMBL81650 0.69 NISCH (0.59) ALDH1A1MEN1KMT2ANISCHMTOR
SCHEMBL10771681 0.68 NISCH (0.39) ALDH1A1MEN1KMT2ANISCHMTOR
SCHEMBL31586399 0.68 NOTUM (0.39) NOTUMTSHR
SCHEMBL28425230 0.67 NISCH (0.56) ALDH1A1MEN1KMT2ANISCHMTOR
Hydrochloric Acid SCHEMBL1536214 0.67 NISCH (0.56) ALDH1A1MEN1KMT2ANISCHMTOR
SCHEMBL29040730 0.67 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ANISCHMTOR
SCHEMBL13977589 0.66 NISCH (0.50) ALDH1A1MEN1KMT2ANISCHMTOR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109651350-B Heterocyclic substituted 1,3,4-oxa (thia) diazoles compound and preparation method and application thereof 贵州大学 2022-05-24 CN disclosed
EP-0913392-B1 ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS NISSAN CHEMICAL IND LTD (JP) 2003-07-02 EP disclosed