Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962204 | 1.00 | KDM1A (0.38) | KDM1AGAAPOLBCYP2C19KMT2A | |
| SCHEMBL21053113 | 0.80 | GRIN2B (0.40) | KDM1AGAAKMT2ARECQLRAB9A | |
| SCHEMBL21053112 | 0.80 | GRIN2B (0.40) | KDM1AGAAKMT2ARECQLRAB9A | |
| SCHEMBL6972040 | 0.77 | NPC1 (0.36) | POLBKMT2ARAB9AMEN1LMNA | |
| SCHEMBL6972037 | 0.77 | NPC1 (0.36) | POLBKMT2ARAB9AMEN1LMNA | |
| SCHEMBL697998 | 0.75 | GFER (0.38) | POLBCYP2C19KMT2ARAB9ALMNA | |
| SCHEMBL696544 | 0.75 | GFER (0.38) | POLBCYP2C19KMT2ARAB9ALMNA | |
| Benzamidoxime SCHEMBL27457742 | 0.75 | POLB (0.58) | KDM1AGAAPOLBCYP2C19KMT2A | |
| SCHEMBL96050 | 0.74 | — | — | |
| SCHEMBL10644432 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |