SCHEMBL6962205

SCHEMBL6962205

c1ccc(Sc2ccsc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2E1 P05181 1/20 0.46
CYP2A6 P11509 1/20 0.46
CYP2B6 P20813 1/20 0.46
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
HPGD P15428 3/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MGLL Q99685 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28206584 0.89 CYP2E1 (0.39) CYP2E1CYP2A6CYP2B6MAOAMAOB
SCHEMBL28243869 0.89 CYP2E1 (0.39) CYP2E1CYP2A6CYP2B6MAOAMAOB
SCHEMBL6665571 0.87 CYP2A6 (0.38) CYP2E1CYP2A6CYP2B6MAPK1LCK
Diphenylsulfane SCHEMBL7109540 0.78 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27611905 0.78 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL452 0.78 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL27714827 0.78 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
Diphenylsulfane SCHEMBL28332331 0.78 HPGD (0.60) MAOAMAOBHPGDMAPTSMN1; SMN2
SCHEMBL7643228 0.76 ICAM1 (0.42) HPGDMAPTSMN1; SMN2HSD17B10ALDH1A1
SCHEMBL4632918 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114797710-A Preparation method of chlorotoluene 常州新东化工发展有限公司 2022-07-29 CN claimed
EP-1181296-A1 CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS ABBOTT LABORATORIES (US) 2002-02-27 EP claimed
WO-2000075145-A1 CELL ADHESION-INHIBITING ANTIINFLAMMATORY COMPOUNDS ABBOTT LABORATORIES (US) 2000-12-14 WO claimed
EP-3157976-B1 COMPOSITION AND METHOD FOR FORMING ELECTROACTIVE POLYMER SOLUTION OR COATING COMPRISING CONJUGATED HETEROAROMATIC POLYMER, ELECTROACTIVE POLYMER SOLUTION, CAPACITOR AND ANTISTATIC OBJECT COMPRISING THE ELECTROACTIVE COATING, AND SOLID ELECTROLYTIC CAPACITOR AND METHOD FOR FABRICATING THE SAME POLYM TECH CORPORATION (TW) 2025-04-16 EP disclosed
CN-114797710-A Preparation method of chlorotoluene 常州新东化工发展有限公司 2022-07-29 CN disclosed
US-10538633-B2 Conjugated heteroaromatic homopolymer and copolymer, and applications thereof POLYM TECHNOLOGY CORPORATION (TW) 2020-01-21 US disclosed
US-10475592-B2 Composition and method for forming electroactive coating comprising conjugated heteroaromatic polymer, capacitor and antistatic object comprising the electroactive coating, and solid electrolytic capacitor and method for fabricating the same POLYM TECHNOLOGY CORPORATION (TW) 2019-11-12 US disclosed
CN-108473822-A Two-stage configuration adhesive binder 3M创新有限公司 2018-08-31 CN disclosed
CN-108026291-A Patterned film product and method comprising cleavable crosslinking agent 3M创新有限公司 2018-05-11 CN disclosed
CN-107683316-A Method of bonding hardware to vehicle glazing 3M创新有限公司 2018-02-09 CN disclosed
US-9859062-B2 Composition and method for forming electroactive polymer solution or coating comprising conjugated heteroaromatic polymer, electroactive polymer solution, capacitor and antistatic object comprising the electroactive coating, and solid electrolytic capacitor and method for fabricating the same POLYM TECHNOLOGY CORPORATION (TW) 2018-01-02 US disclosed
US-5962490-A Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin TEXAS BIOTECHNOLOGY CORPORATION (US) 1999-10-05 US disclosed
EP-0819125-A1 THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1998-01-21 EP disclosed
US-5594021-A VASOCONSTRICTORS TEXAS BIOTECHNOLOGY CORPORATION (US) 1997-01-14 US disclosed
WO-1996031492-A1 THIENYL-, FURYL-, PYRROLYL- AND BIPHENYLSULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN TEXAS BIOTECHNOLOGY CORPORATION (US) 1996-10-10 WO disclosed
US-4994485-A Seed and soil fungi, bacteria DUPHAR INTERNATIONAL RESEARCH B.V. (NL) 1991-02-19 US disclosed
EP-0234622-B1 NEW THIO COMPOUNDS HAVING FUNGICIDAL ACTIVITY DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1990-06-27 EP disclosed
US-4711742-A Solution processible forms of neutral and electrically conductive poly(substituted heterocycles) ALLIED CORPORATION (US) 1987-12-08 US disclosed
EP-0203438-A1 Solution processible forms of neutral and electrically conductive poly(substituted heterocycles) ALLIED CORPORATION (US) 1986-12-03 EP disclosed
US-4294838-A ANTIBRONCHOSPASMOLYTIC AGENTS WARNER-LAMBERT COMPANY, A CORP. OF DE 1981-10-13 US disclosed