Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962205 | 0.87 | CYP2E1 (0.46) | CYP2A6CYP2B6CYP2E1LCKFYN | |
| SCHEMBL11381667 | 0.84 | CYP2A6 (0.36) | CYP2A6CYP2B6L3MBTL1CES2CES1 | |
| SCHEMBL177835 | 0.83 | CYP3A4 (0.64) | TAAR1CYP3A4NR1H2TSHRMAPK1 | |
| SCHEMBL29521773 | 0.79 | CYP2A6 (0.33) | CYP2A6CYP2B6L3MBTL1CES2CES1 | |
| SCHEMBL1146010 | 0.79 | — | — | |
| SCHEMBL28867994 | 0.79 | CYP2A6 (0.33) | CYP2A6CYP2B6L3MBTL1CES2CES1 | |
| SCHEMBL28243869 | 0.78 | CYP2E1 (0.39) | CYP2A6CYP2B6CYP2E1MAPK1 | |
| SCHEMBL28206584 | 0.78 | CYP2E1 (0.39) | CYP2A6CYP2B6CYP2E1MAPK1 | |
| SCHEMBL19220746 | 0.77 | — | — | |
| SCHEMBL28017676 | 0.77 | L3MBTL1 (0.32) | CYP2A6CYP2B6L3MBTL1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107115383-B | Skin care/treatment composition having skin xerosis syndrome preventing and treating effect | 成都华西珐玛生物科技有限公司 | 2021-04-27 | — | — | CN | disclosed |
| CN-107260811-B | Skin care/treatment composition with acne prevention and treatment effects | 成都华西珐玛生物科技有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-107158086-B | Skin care/treatment composition having itch relieving effect | 成都华西珐玛生物科技有限公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-110857385-A | Composition and preparation method and application thereof | 科思创德国股份有限公司 | 2020-03-03 | — | — | CN | disclosed |
| CN-104725172-B | A kind of synthetic method of aryl thioethers class compound | 华东师范大学 | 2017-03-01 | — | — | CN | disclosed |
| CN-104725172-A | Synthetic method of aryl sulfide type compound | UNIV EAST CHINA NORMAL | 2015-06-24 | — | — | CN | disclosed |
| US-20090137789-A1 | Oligonucleotide Probes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2009-05-28 | — | — | US | disclosed |
| US-20090137789-A1 | Oligonucleotide Probes | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 2009-05-28 | — | — | US | disclosed |
| EP-0910362-B1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-0910331-B1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PROD INC (US) | 2004-09-08 | — | — | EP | disclosed |
| US-5847003-A | Oxa acids and related compounds for treating skin conditions | AVON PRODUCTS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998050004-A1 | ASCORBYL-PHOSPHORYL-CHOLESTEROL | AVON PRODUCTS, INC. (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5834513-A | TOPICAL COMPOSITION FOR TREATING SKIN CONDITIONS CHARACTERIZED BY ABNORMAL DESQUAMATION | AVON PRODUCTS, INC. (US) | 1998-11-10 | — | — | US | disclosed |
| WO-1997046231-A1 | OXA ACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-12-11 | — | — | WO | disclosed |
| WO-1997039726-A1 | OXA DIACIDS AND RELATED COMPOUNDS FOR TREATING SKIN CONDITIONS | AVON PRODUCTS, INC. (US) | 1997-10-30 | — | — | WO | disclosed |
| EP-0073562-B1 | HERBICIDAL TRIAZOLE UREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-09 | — | — | EP | disclosed |
| US-4425155-A | 1,2,4-TRIAZINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-10 | — | — | US | disclosed |
| US-4421550-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-20 | — | — | US | disclosed |
| EP-0073562-A2 | Herbicidal triazole ureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |
| US-4294838-A | ANTIBRONCHOSPASMOLYTIC AGENTS | WARNER-LAMBERT COMPANY, A CORP. OF DE | 1981-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137789-A1 | Oligonucleotide Probes | NCL, RNGTT, NSUN3 | CYP2A6 3506/4885CYP2B6 2532/4885L3MBTL1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.