Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953530 | 0.91 | GCGR (0.38) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6961362 | 0.89 | GCGR (0.35) | GCGR | |
| SCHEMBL6958555 | 0.86 | GCGR (0.61) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6963303 | 0.86 | GCGR (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6961105 | 0.85 | GCGR (0.50) | GCGR | |
| SCHEMBL2647300 | 0.85 | GCGR (0.56) | GCGR | |
| SCHEMBL6953892 | 0.84 | GCGR (0.61) | GCGR | |
| SCHEMBL6962775 | 0.83 | GCGR (0.48) | GCGR | |
| SCHEMBL6957684 | 0.82 | GCGR (0.46) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6961744 | 0.81 | GCGR (0.45) | GCGRESR1HMGCRCHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325130-B1 | Substituted pyridines | BAYER AG (DE) | 2003-11-05 | — | — | EP | disclosed |
| EP-1123925-A1 | Process for preparation of substituted pyridines | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| EP-1123924-A1 | Substituted pyridines as HMG-COA reductase inhibitors | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |