Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 19/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962452 | 0.91 | GCGR (0.45) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL8953339 | 0.88 | GCGR (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL9152690 | 0.86 | GCGR (0.50) | GCGR | |
| SCHEMBL6961362 | 0.85 | GCGR (0.35) | GCGR | |
| SCHEMBL9410045 | 0.85 | GCGR (0.50) | GCGR | |
| SCHEMBL6961105 | 0.80 | GCGR (0.50) | GCGR | |
| SCHEMBL6958555 | 0.79 | GCGR (0.61) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6963303 | 0.77 | GCGR (0.50) | GCGRESR1HMGCRCHRM1TBXA2R | |
| SCHEMBL6953892 | 0.77 | GCGR (0.61) | GCGR | |
| SCHEMBL6962775 | 0.76 | GCGR (0.48) | GCGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603649-B1 | Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines as HMG-CoA reductase inhibitors | BAYER AG (DE) | 1996-07-10 | — | — | EP | disclosed |
| EP-0603649-A1 | Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridines as HMG-CoA reductase inhibitors | BAYER AG (DE) | 1994-06-29 | — | — | EP | disclosed |