Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962440 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1HPGDTDP1CNR1 | |
| SCHEMBL6963527 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2NPSR1TDP1CNR1EPHX2 | |
| SCHEMBL9749994 | 0.75 | POLB (0.55) | SMN1; SMN2ALDH1A1HPGDTDP1POLB | |
| SCHEMBL10640646 | 0.72 | MAPT (0.60) | SMN1; SMN2ALDH1A1HPGDTDP1POLB | |
| SCHEMBL9667225 | 0.71 | SMN1; SMN2 (0.67) | SMN1; SMN2NPSR1CNR1EPHX2MAOB | |
| SCHEMBL6962595 | 0.71 | ALDH1A1 (0.52) | SMN1; SMN2NPSR1ALDH1A1TDP1CNR1 | |
| SCHEMBL11527915 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2NPSR1ALDH1A1HPGDTDP1 | |
| SCHEMBL14049512 | 0.67 | SMN1; SMN2 (0.70) | SMN1; SMN2NPSR1CNR1EPHX2MAOB | |
| SCHEMBL8350625 | 0.67 | SMN1; SMN2 (0.70) | SMN1; SMN2NPSR1CNR1EPHX2MAOB | |
| SCHEMBL13923628 | 0.67 | SMN1; SMN2 (0.70) | SMN1; SMN2NPSR1CNR1EPHX2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |