Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 17/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962894 | 1.00 | HTR1A (1.00) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL6963912 | 1.00 | HTR1A (1.00) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL6962900 | 1.00 | HTR1A (1.00) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL6964918 | 0.87 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6973696 | 0.87 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6972638 | 0.87 | HTR1A (0.79) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL6972641 | 0.87 | HTR1A (0.79) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL6972644 | 0.87 | HTR1A (0.79) | HTR1AALDH1A1LMNACYP3A4ALOX12 | |
| SCHEMBL6964920 | 0.87 | HTR1A (1.00) | HTR1A | |
| SCHEMBL6964927 | 0.87 | HTR1A (1.00) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906912-B1 | Indanol derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-01-08 | — | — | EP | disclosed |
| US-6060487-A | Indanol compounds | ADIR ET COMPAGNIE (FR) | 2000-05-09 | — | — | US | disclosed |
| EP-0906912-A1 | Indanol derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-04-07 | — | — | EP | disclosed |