Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | PARP16 | Q8N5Y8 | 2/20 | 0.30 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962994 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTNR3C1NPC1 | |
| SCHEMBL6962740 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2NR3C1KDM1AMAOAMAOB | |
| SCHEMBL6962739 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2NR3C1KDM1AMAOAMAOB | |
| SCHEMBL6959944 | 0.81 | NPC1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6959941 | 0.81 | NPC1 (0.46) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6958678 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6958684 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6953879 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6953875 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL6962449 | 0.73 | NPC1 (0.49) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5714503-A | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 1998-02-03 | — | — | US | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |
| WO-1993003022-A1 | COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES | MEDIVIR AB (SE) | 1993-02-18 | — | — | WO | disclosed |