Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.64 |
| ▸ | BRD4 | O60885 | 9/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907051 | 0.91 | MAPK14 (0.77) | MAPK14BRD4BRDTBRD2BRD3 | |
| SCHEMBL4593693 | 0.88 | MAPK14 (0.81) | MAPK14BRD4BRDTBRD2BRD3 | |
| SCHEMBL7715290 | 0.80 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL6957344 | 0.78 | MAPK14 (1.00) | MAPK14BRD4BRDTBRD2BRD3 | |
| SCHEMBL4585936 | 0.77 | MAPK14 (0.53) | MAPK14BRDT | |
| SCHEMBL8524327 | 0.77 | MAPK14 (0.59) | MAPK14BRD4BRDTBRD2BRD3 | |
| SCHEMBL8162468 | 0.76 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL4602363 | 0.76 | MAPK14 (0.52) | MAPK14BRDT | |
| SCHEMBL7907043 | 0.75 | MAPK14 (0.56) | MAPK14BRD4BRDTBRD2BRD3 | |
| SCHEMBL7767922 | 0.71 | MAPK14 (0.63) | MAPK14BRD4BRDT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831830-B1 | IMIDAZOLE COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2003-03-05 | — | — | EP | disclosed |