Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL695900 | 0.88 | TDP1 (0.54) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL696289 | 0.88 | TDP1 (0.54) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL697926 | 0.86 | RAB9A (0.48) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL697359 | 0.85 | TDP1 (0.47) | TDP1CYP19A1LMNACYP1A2CYP2D6 | |
| SCHEMBL703762 | 0.84 | TDP1 (0.44) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL697205 | 0.83 | TDP1 (0.44) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL698831 | 0.82 | TDP1 (0.43) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL697990 | 0.82 | TDP1 (0.46) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL698832 | 0.82 | TDP1 (0.44) | TDP1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL704903 | 0.81 | TDP1 (0.40) | TDP1LMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |