Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CHKA | P35790 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL209616 | 1.00 | GAA (0.63) | GAABIRC2CA2CHKACHRM5 | |
| SCHEMBL254801 | 0.98 | GAA (0.67) | GAABIRC2CA2CHKACHRM5 | |
| Hydrochloric Acid SCHEMBL27822626 | 0.98 | GAA (0.61) | GAABIRC2CA2CHKACHRM5 | |
| SCHEMBL655825 | 0.92 | GAA (0.69) | GAABIRC2CA2CHKACHRM5 | |
| SCHEMBL361321 | 0.91 | GAA (0.56) | GAABIRC2CA2CHKACHRM5 | |
| SCHEMBL758408 | 0.90 | GAA (0.73) | GAABIRC2CA2CHKACHRM5 | |
| Hydrochloric Acid SCHEMBL8186264 | 0.90 | GAA (0.67) | GAABIRC2CA2CHKACHRM5 | |
| SCHEMBL4000321 | 0.84 | GAA (0.50) | GAABIRC2CHRM5CHRM3TSHR | |
| SCHEMBL3440531 | 0.84 | GAA (0.86) | GAABIRC2TSHRALOX15HSD17B10 | |
| SCHEMBL8729488 | 0.84 | CHRM5 (0.79) | GAABIRC2CA2CHKACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620216-B1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-5521170-A | VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0620216-A1 | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |