Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CHKA | P35790 | 1/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655825 | 0.98 | GAA (0.69) | GAACA2CHKABIRC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8186264 | 0.96 | GAA (0.67) | GAACA2CHKABIRC2ALDH1A1 | |
| SCHEMBL254801 | 0.92 | GAA (0.67) | GAACA2CHKABIRC2ALDH1A1 | |
| SCHEMBL209616 | 0.90 | GAA (0.63) | GAACA2CHKABIRC2ALDH1A1 | |
| SCHEMBL6963350 | 0.90 | GAA (0.63) | GAACA2CHKABIRC2ALDH1A1 | |
| SCHEMBL361321 | 0.90 | GAA (0.56) | GAACA2CHKABIRC2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27822626 | 0.88 | GAA (0.61) | GAACA2CHKABIRC2ALDH1A1 | |
| SCHEMBL20349175 | 0.85 | GAA (0.91) | GAABIRC2ALDH1A1MAPTALOX15 | |
| SCHEMBL21338467 | 0.85 | GAA (0.91) | GAABIRC2ALDH1A1MAPTALOX15 | |
| SCHEMBL3912798 | 0.85 | GAA (0.91) | GAABIRC2ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120053345-A1 | Indazole Compounds | ABBOTT LABORATORIES (US) | 2012-03-01 | — | — | US | disclosed |
| US-8008481-B2 | Indazole compounds | ABBVIE INC. | 2011-08-30 | — | — | US | disclosed |
| US-20070282101-A1 | Indazole compounds | ABBVIE INC. | 2007-12-06 | — | — | US | disclosed |
| EP-0132764-A2 | Derivatives of dihydrodibenzocycloheptylidene-ethylamine | SOCIEDAD ESPANOLA DE ESPECIALIDADES FARMACO-TERAPEUTICAS, S.A. (ES) | 1985-02-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070282101-A1 | Indazole compounds | CYP3A43, CYP3A7, UGT1A1 | GAA 358/4885CA2 3954/4885CHKA 1540/4885 |
| US-20120053345-A1 | Indazole Compounds | CYP3A43, CYP3A7, UGT1A1 | GAA 358/4885CA2 3954/4885CHKA 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.