Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.73 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.73 |
| ▸ | MAOB | P27338 | 8/20 | 0.72 |
| ▸ | MAOA | P21397 | 4/20 | 0.68 |
| ▸ | TYR | P14679 | 2/20 | 0.68 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.66 |
| ▸ | JAK2 | O60674 | 1/20 | 0.66 |
| ▸ | STK17B | O94768 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30214393 | 1.00 | MEN1 (0.74) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL28949983 | 1.00 | MEN1 (0.74) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL6963496 | 0.89 | MEN1 (0.80) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL6963493 | 0.89 | MEN1 (0.80) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL21046449 | 0.85 | MEN1 (1.00) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5707772 | 0.85 | MAOB (0.83) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5707779 | 0.85 | MAOB (0.83) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL19498882 | 0.83 | STK17B (0.69) | MEN1KMT2AMAOBMAOARECQL | |
| SCHEMBL10913601 | 0.82 | MEN1 (0.70) | MEN1KMT2APOLBRAB9AUSP2 | |
| SCHEMBL5707753 | 0.82 | TYR (1.00) | MEN1KMT2APOLBRAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677635-B | Orange ketone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2024-04-09 | — | — | CN | disclosed |
| CN-115677635-A | Aurone derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-02-03 | — | — | CN | disclosed |