Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958269 | 0.93 | GAA (0.48) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6953108 | 0.90 | GAA (0.51) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6956121 | 0.87 | KMT2A (0.45) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL9057398 | 0.87 | GAA (0.51) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6956612 | 0.86 | PHGDH (0.40) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8699871 | 0.84 | GAA (0.48) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL5396710 | 0.84 | HCAR2 (0.48) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6960154 | 0.80 | GAA (0.48) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6965432 | 0.80 | KMT2A (0.53) | GAAKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL6961290 | 0.79 | KMT2A (0.46) | GAAKMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |