Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700453 | 0.90 | RBP4 (0.56) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL8704931 | 0.90 | RBP4 (0.57) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL8703619 | 0.90 | GAA (0.48) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL8703466 | 0.89 | MAPT (0.48) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL9057398 | 0.89 | GAA (0.51) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL8699082 | 0.89 | KMT2A (0.48) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL8704635 | 0.89 | KMT2A (0.52) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL8699350 | 0.88 | KMT2A (0.53) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL6958269 | 0.88 | GAA (0.48) | GAAKMT2ALMNAHSD17B10POLB | |
| SCHEMBL9016354 | 0.87 | CA12 (0.41) | GAAKMT2ALMNAHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |