Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573354 | 0.86 | TAAR1 (0.40) | TAAR1CYP19A1ALDH1A1SMN1; SMN2F2RL1 | |
| SCHEMBL696761 | 0.84 | TAAR1 (0.40) | TAAR1CYP19A1F2RL1GABRA1GABRB2 | |
| SCHEMBL697647 | 0.83 | CYP19A1 (0.38) | CYP19A1ALDH1A1SMN1; SMN2NISCHNPC1 | |
| SCHEMBL697421 | 0.82 | CYP19A1 (0.41) | TAAR1CYP19A1ALDH1A1SMN1; SMN2F2RL1 | |
| SCHEMBL699180 | 0.80 | CYP19A1 (0.47) | TAAR1CYP19A1ALDH1A1SMN1; SMN2F2RL1 | |
| SCHEMBL697724 | 0.78 | TAAR1 (0.46) | TAAR1CYP19A1ALDH1A1F2RL1HTR1A | |
| SCHEMBL697230 | 0.77 | CYP19A1 (0.40) | CYP19A1ALDH1A1SMN1; SMN2F2RL1 | |
| SCHEMBL705114 | 0.76 | CYP19A1 (0.42) | TAAR1CYP19A1ALDH1A1SMN1; SMN2NISCH | |
| SCHEMBL6302051 | 0.76 | CYP19A1 (0.47) | TAAR1CYP19A1ALDH1A1NISCHMTOR | |
| SCHEMBL697087 | 0.76 | CYP19A1 (0.47) | TAAR1CYP19A1ALDH1A1NISCHMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |