Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696368 | 0.84 | TAAR1 (0.42) | TAAR1CYP19A1F2RL1GABRA1GABRB2 | |
| SCHEMBL1573354 | 0.83 | TAAR1 (0.40) | TAAR1CYP19A1F2RL1GABRA1GABRB2 | |
| SCHEMBL697775 | 0.81 | TAAR1 (0.44) | TAAR1CYP19A1PARP1HSD11B1 | |
| SCHEMBL696829 | 0.81 | TAAR1 (0.44) | TAAR1CYP19A1F2RL1PARP1 | |
| SCHEMBL699180 | 0.81 | CYP19A1 (0.47) | TAAR1CYP19A1F2RL1GABRA1GABRB2 | |
| SCHEMBL697435 | 0.80 | CYP19A1 (0.46) | TAAR1CYP19A1PARP1 | |
| SCHEMBL697724 | 0.78 | TAAR1 (0.46) | TAAR1CYP19A1F2RL1GABRA1GABRB2 | |
| SCHEMBL697634 | 0.78 | CYP19A1 (0.37) | TAAR1CYP19A1F2RL1 | |
| SCHEMBL697917 | 0.76 | CYP19A1 (0.38) | TAAR1CYP19A1F2RL1HSD11B1 | |
| SCHEMBL1573181 | 0.76 | CYP19A1 (0.40) | TAAR1CYP19A1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| CN-101370786-A | Substituted imidazoles and their use as pesticides | PFIZER LTD (GB) | 2009-02-18 | — | — | CN | disclosed |