Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.49 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9051963 | 0.86 | CYSLTR1 (0.52) | CYSLTR1CYSLTR2RAB9AGPBAR1 | |
| SCHEMBL8783748 | 0.82 | TACR2 (0.43) | CYSLTR1CYSLTR2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL3271327 | 0.82 | CYSLTR1 (0.69) | CYSLTR1CYSLTR2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8878133 | 0.81 | CYSLTR1 (0.51) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL8876557 | 0.80 | CYSLTR1 (0.68) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL8632598 | 0.79 | CYSLTR1 (0.49) | CYSLTR1CYSLTR2PDE10AGPBAR1 | |
| SCHEMBL16838753 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2RAB9AL3MBTL1 | |
| SCHEMBL9031842 | 0.78 | CYSLTR1 (0.64) | CYSLTR1CYSLTR2ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9054127 | 0.78 | FFAR1 (0.55) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL8783877 | 0.77 | CYSLTR1 (0.43) | CYSLTR1CYSLTR2PDE10AGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902007-B1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6046212-A | ANTIALLERGIC AGENTS | KOWA CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0902007-A1 | CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME | KOWA CO. LTD. (JP) | 1999-03-17 | — | — | EP | disclosed |