Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.42 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.42 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.42 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810966 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AALOX15TSHR | |
| SCHEMBL7260391 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL28189359 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL22410702 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL27637998 | 0.80 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL3591615 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL2200894 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL2230388 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL29642602 | 0.77 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL2812139 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2APDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0787725-B1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1071333-C | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 2001-09-19 | — | — | CN | disclosed |
| CN-1170411-A | Quinoline derivative | NIPPON CHEMIPHAR CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| US-5693651-A | HYPOGLYCEMIC AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0787725-A1 | QUINOLINE DERIVATIVE | NIPPON CHEMIPHAR CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |