Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | JUN | P05412 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1470493 | 0.84 | SMN1; SMN2 (0.58) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL8787255 | 0.81 | SMN1; SMN2 (0.56) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL10370773 | 0.81 | CYP2A6 (0.66) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL1233284 | 0.80 | CYP2A6 (0.63) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL3070140 | 0.78 | CYP2A6 (0.61) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL12174999 | 0.78 | CYP2A6 (0.61) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL6710511 | 0.78 | CYP2A6 (0.61) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL6979554 | 0.78 | CYP2A6 (0.61) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL5291945 | 0.78 | SMN1; SMN2 (0.55) | CYP2A6SMN1; SMN2TP53RXFP1MAPT | |
| SCHEMBL6673016 | 0.77 | CYP2A6 (0.59) | CYP2A6SMN1; SMN2TP53RXFP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |