Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | GLS | O94925 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991380 | 0.86 | KMT2A (0.54) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL2586902 | 0.86 | CYP3A4 (0.53) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL29639215 | 0.86 | KMT2A (0.54) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL27336582 | 0.84 | KMT2A (0.52) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL1032325 | 0.84 | CA12 (0.50) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL2532788 | 0.84 | KMT2A (0.49) | KMT2AMEN1GLSALDH1A1HIF1A | |
| Hydrochloric Acid SCHEMBL2532791 | 0.84 | KMT2A (0.55) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL710329 | 0.83 | LMNA (0.56) | KMT2AMEN1ATMTSHRLMNA | |
| SCHEMBL10714737 | 0.83 | KMT2A (0.55) | KMT2AMEN1GLSALDH1A1HIF1A | |
| SCHEMBL11230181 | 0.81 | KMT2A (0.47) | KMT2AMEN1GLSALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |