Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19700319 | 1.00 | NOX1 (0.52) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL8172158 | 1.00 | NOX1 (0.52) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4651367 | 1.00 | NOX1 (0.52) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL13979705 | 0.92 | RELA (0.51) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4650606 | 0.92 | RELA (0.51) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4652218 | 0.92 | RELA (0.51) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4650607 | 0.92 | RELA (0.51) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL4652223 | 0.92 | RELA (0.51) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9707139 | 0.91 | NOX1 (0.45) | NOX1MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9707136 | 0.91 | NOX1 (0.45) | NOX1MAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095937-B1 | Process for the preparation of trisubstituted oxazoles | OREAL (FR) | 2003-03-12 | — | — | EP | disclosed |
| US-6333414-B1 | BY REACTION OF THIOUREA WITH THE CORRESPONDING DIKETONE ESTER; CARRIED OUT UNDER REACTION CONDITIONS, PARTICULARLY WITH RESPECT TO PH, WHICH ARE INDUSTRIALLY MORE FAVORABLE. | L'ORéAL S.A. (FR) | 2001-12-25 | — | — | US | disclosed |
| EP-1095937-A1 | Process for the preparation of trisubstituted oxazoles | L'OREAL (FR) | 2001-05-02 | — | — | EP | disclosed |
| US-4431722-A | POLYCYCLIC QUINONE PIGMENT DISPERSED IN A RESIN BINDER AS CHARGE GENERATING LAYER; ANTIFOGGING AGENTS | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-02-14 | — | — | US | disclosed |