Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697231 | 0.89 | CYP19A1 (0.38) | CYP19A1ALDH1A1SMN1; SMN2MDM2MAP3K14 | |
| SCHEMBL705114 | 0.84 | CYP19A1 (0.42) | CYP19A1ALDH1A1SMN1; SMN2MDM2NISCH | |
| SCHEMBL697304 | 0.83 | CYP19A1 (0.50) | CYP19A1ALDH1A1SMN1; SMN2MDM2NISCH | |
| SCHEMBL697276 | 0.81 | CYP19A1 (0.41) | CYP19A1ALDH1A1SMN1; SMN2MDM2MAP3K14 | |
| SCHEMBL697647 | 0.81 | CYP19A1 (0.38) | CYP19A1ALDH1A1SMN1; SMN2NISCHNPC1 | |
| SCHEMBL697087 | 0.77 | CYP19A1 (0.47) | CYP19A1ALDH1A1NISCHTAAR1 | |
| SCHEMBL6302051 | 0.77 | CYP19A1 (0.47) | CYP19A1ALDH1A1NISCHTAAR1 | |
| SCHEMBL697864 | 0.76 | CYP19A1 (0.48) | CYP19A1MDM2MAP3K14 | |
| SCHEMBL697370 | 0.76 | CYP19A1 (0.51) | CYP19A1ALDH1A1SMN1; SMN2MDM2 | |
| SCHEMBL697576 | 0.76 | CYP19A1 (0.40) | CYP19A1ALDH1A1SMN1; SMN2NISCHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |