Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.30 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.30 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL696482 | 0.85 | CYP19A1 (0.44) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL697304 | 0.79 | CYP19A1 (0.50) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL697647 | 0.78 | CYP19A1 (0.38) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1573354 | 0.77 | TAAR1 (0.40) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL705114 | 0.77 | CYP19A1 (0.42) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL697369 | 0.77 | ADRA2A (0.43) | CYP19A1SMN1; SMN2ALDH1A1ADRA2AADRA2C | |
| SCHEMBL696424 | 0.76 | CYP19A1 (0.42) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL699180 | 0.75 | CYP19A1 (0.47) | CYP19A1SMN1; SMN2ALDH1A1CASRADRA2A | |
| SCHEMBL699118 | 0.75 | CYP19A1 (0.50) | CYP19A1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL696368 | 0.74 | TAAR1 (0.42) | CYP19A1NISCHNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |