Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 12/20 | 0.47 |
| ▸ | PPARA | Q07869 | 12/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972841 | 0.85 | FFAR1 (0.58) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL5380575 | 0.83 | FFAR1 (0.69) | FFAR1PPARGPPARAKDR | |
| SCHEMBL6965302 | 0.82 | FFAR1 (0.52) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL6970759 | 0.81 | FFAR1 (0.61) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL6963887 | 0.80 | FFAR1 (0.54) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL8845954 | 0.80 | FFAR1 (0.50) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL4029049 | 0.78 | KDR (0.64) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL7162113 | 0.78 | FFAR1 (0.54) | FFAR1PPARGPPARAMAPTKDR | |
| SCHEMBL6203880 | 0.78 | FFAR1 (0.59) | FFAR1PPARGPPARA | |
| SCHEMBL6957652 | 0.77 | FFAR1 (0.51) | FFAR1PPARGPPARAMAPTKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0629624-B1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |