Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 17/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417412 | 0.83 | F2 (0.52) | LTA4H | |
| Oxalic Acid SCHEMBL7417461 | 0.79 | F2 (0.50) | — | |
| SCHEMBL7949758 | 0.79 | HRH3 (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL6957964 | 0.77 | LTA4H (0.45) | LTA4HHRH3 | |
| SCHEMBL7407832 | 0.76 | ESR1 (0.62) | — | |
| SCHEMBL7442242 | 0.76 | LTA4H (0.69) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| Oxalic Acid SCHEMBL7411155 | 0.74 | ESR1 (0.62) | — | |
| SCHEMBL6964901 | 0.72 | LTA4H (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7349591 | 0.72 | LTA4H (0.70) | LTA4HHRH3PSMB1PSMB5PSMB2 | |
| SCHEMBL7444253 | 0.72 | LTA4H (0.61) | LTA4HHRH3PSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980367-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0980367-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049161-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |