Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.40 |
| ▸ | RELA | Q04206 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28619274 | 0.81 | HPGD (0.47) | RAB9ANPC1SMN1; SMN2MAPTTP53 | |
| SCHEMBL2225025 | 0.81 | KDM4E (0.43) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6965803 | 0.81 | HDAC1 (0.50) | HDAC1HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL2224915 | 0.79 | DRD2 (0.50) | HDAC1HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL6975567 | 0.78 | HDAC1 (0.51) | HDAC1HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL2224617 | 0.76 | HDAC1 (0.44) | HDAC1HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL24742228 | 0.76 | IDH1 (0.39) | MAPTL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL6971887 | 0.76 | HDAC1 (0.56) | HDAC1HDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL29987532 | 0.76 | IDH1 (0.39) | MAPTL3MBTL1TSHRKMT2AMEN1 | |
| SCHEMBL15752407 | 0.72 | PDE4B (0.39) | RAB9ANPC1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206457-B1 | BIARYL-OXA(THIA)ZOLE DERIVATIVES AND THEIR USE AS PPARS MODULATORS | LILLY CO ELI (US) | 2003-10-15 | — | — | EP | claimed |