Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14527716 | 1.00 | CACNA1B (0.33) | CACNA1BNPSR1 | |
| SCHEMBL6960090 | 1.00 | CACNA1B (0.33) | CACNA1BNPSR1 | |
| SCHEMBL17039350 | 0.98 | CACNA1B (0.32) | CACNA1B | |
| SCHEMBL17039354 | 0.93 | — | — | |
| SCHEMBL17039353 | 0.88 | — | — | |
| SCHEMBL17039473 | 0.78 | — | — | |
| SCHEMBL20730464 | 0.77 | SHBG (0.31) | — | |
| SCHEMBL17036750 | 0.77 | — | — | |
| SCHEMBL8909887 | 0.76 | NPSR1 (0.32) | NPSR1 | |
| SCHEMBL13845702 | 0.75 | TEAD2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891331-B1 | N-(2 OXOACETYL OR SULPHONYL)-PYRROLIDINE/PIPERIDINE-2-CARBOXYLIC ACID DERIVATIVES WITH IMPROVED MULTI-DRUG RESISTANCE ACTIVITY | VERTEX PHARMA (US) | 2003-10-01 | — | — | EP | disclosed |