Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962128 | 0.86 | RBP4 (0.47) | MAPTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL6966587 | 0.84 | RBP4 (0.52) | MAPTSMN1; SMN2KDM4ETP53HSD17B10 | |
| SCHEMBL6960606 | 0.82 | KMT2A (0.56) | MAPTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8699252 | 0.78 | MAPT (0.44) | MAPTSMN1; SMN2KDM4EPANK3TP53 | |
| SCHEMBL26758580 | 0.72 | KDM4E (0.48) | MAPTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL6781384 | 0.72 | RBP4 (0.57) | MAPTKDM4ETP53PKMHSD17B10 | |
| SCHEMBL8699306 | 0.71 | MAPT (0.42) | MAPTSMN1; SMN2KDM4ETP53PKM | |
| SCHEMBL6956352 | 0.71 | MAPT (0.44) | MAPTSMN1; SMN2KDM4ETP53PKM | |
| SCHEMBL23806110 | 0.71 | MAPT (0.70) | MAPTSMN1; SMN2CA12CA1CA2 | |
| SCHEMBL6960605 | 0.71 | RBP4 (0.54) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850222-B1 | PIPERAZINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARM CO LTD (KR) | 2003-05-28 | — | — | EP | disclosed |
| US-6028195-A | AN ANTITUMOR AGENT WITH VERY LOW TOXICITIES | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-02-22 | — | — | US | disclosed |