SCHEMBL6964934

SCHEMBL6964934

[CH2]COC(=O)c1ccc(Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.53
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
MAPT P10636 4/20 0.47
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GSK3B P49841 2/20 0.47
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.45
CHRNB2 P17787 1/20 0.45
CHRNA5 P30532 1/20 0.45
CHRNA7 P36544 1/20 0.45
CHRNA4 P43681 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811579 0.83 GAA (0.66) GAAALDH1A1MEN1KMT2ACES2
SCHEMBL8680201 0.81 GAA (0.54) GAAALDH1A1MEN1KMT2ACES2
SCHEMBL10376725 0.81 GSK3B (0.57) GAAALDH1A1MEN1KMT2ACES2
SCHEMBL8680210 0.81 GAA (0.54) GAAALDH1A1MEN1KMT2ACES2
SCHEMBL8679315 0.81 GAA (0.54) GAAALDH1A1MEN1KMT2ACES2
SCHEMBL7971504 0.80 KMT2A (0.53) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL8743221 0.79 HPGD (0.56) ALDH1A1MEN1KMT2ACES2CES1
SCHEMBL8742866 0.79 TDP1 (0.57) GAAALDH1A1KMT2ACES2CES1
SCHEMBL11320755 0.79 CA1 (0.57) GAAALDH1A1MEN1KMT2AMAPT
SCHEMBL203843 0.79 CA12 (0.68) GAAALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4624698-A Herbicidal tetrahydrobenzothiazolyl-1,3,5-triazinone derivatives and compositions thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-11-25 US claimed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP disclosed
EP-0508549-B1 New triazolopyrimidine and pyrazolopyrimidine derivatives useful for treating cachexia SANKYO CO (JP) 1995-04-26 EP disclosed
EP-0460463-B1 Use of azo dyes in thermal transfer printing BASF AG (DE) 1994-12-14 EP disclosed
EP-0344487-B1 Azo dyes of the 5-aminoisothiazole series BASF AG (DE) 1993-12-29 EP disclosed
EP-0347252-B1 METHOD OF TREATING CACHEXIA AND CERTAIN NEW COMPOUNDS FOR USE IN THIS METHOD SANKYO COMPANY LIMITED (JP) 1993-05-05 EP disclosed
US-5200386-A Heating to deffuse from transfer sheet to plastic-coated substrate BASF AKTIENGESELLSCHAFT (DE) 1993-04-06 US disclosed
EP-0508549-A2 New triazolopyrimidine and pyrazolopyrimidine derivatives useful for treating cachexia SANKYO COMPANY LIMITED (JP) 1992-10-14 EP disclosed
US-5086057-A METHOD OF TREATING CACHEXIA AND CERTAIN NEW COMPOUNDS FOR USE IN THIS METHOD SANKYO COMPANY LIMITED (JP) 1992-02-04 US disclosed
EP-0460463-A1 Use of azo dyes in thermal transfer printing BASF Aktiengesellschaft (DE) 1991-12-11 EP disclosed
EP-0347252-A2 Method of treating cachexia and certain new compounds for use in this method SANKYO COMPANY LIMITED (JP) 1989-12-20 EP disclosed
EP-0344487-A2 Azo dyes of the 5-aminoisothiazole series BASF Aktiengesellschaft (DE) 1989-12-06 EP disclosed
US-4624698-A Herbicidal tetrahydrobenzothiazolyl-1,3,5-triazinone derivatives and compositions thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-11-25 US disclosed
US-4624698-A Herbicidal tetrahydrobenzothiazolyl-1,3,5-triazinone derivatives and compositions thereof KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-11-25 US disclosed
US-4551467-A Vasodilating cyanoalkyl esters of 1,4-dihydropyridines BAYER AKTIENGESELLSCHAFT (DE) 1985-11-05 US disclosed
US-4283331-A FIBER-REACTIVE DYES CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4243809-A 5-SULFONYL-6-HYDROXYPYRIDONES OR THE 3-CARBAMOYL DERIVATIVES; SULFONYLATION WITH AN ALKYL SULFONYL HALIDE CIBA-GEIGY CORPORATION (US) 1981-01-06 US disclosed
US-4241208-A STABILIZERS OF SYNTHETIC POLYMERS AGAINST HEAT AND LIGHT SANKYO COMPANY LIMITED (JP) 1980-12-23 US disclosed
US-4066615-A PHOTOSTABILITY, THERMAL STABILITY SANKYO COMPANY LIMITED (JA) 1978-01-03 US disclosed
US-3941744-A SYNTHETIC RESIN SANKYO COMPANY LIMITED (JA) 1976-03-02 US disclosed