Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.60 |
| ▸ | CNR1 | P21554 | 9/20 | 0.60 |
| ▸ | ACHE | P22303 | 7/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27529329 | 0.87 | CNR2 (0.61) | CNR2CNR1ACHEBCHEMGLL | |
| SCHEMBL6973326 | 0.78 | CNR2 (0.58) | CNR2CNR1ACHEBCHEMGLL | |
| SCHEMBL6969602 | 0.77 | CNR2 (0.52) | CNR2CNR1ACHEMAPTSMN1; SMN2 | |
| SCHEMBL7116425 | 0.75 | CNR2 (1.00) | CNR2CNR1ACHEBCHE | |
| SCHEMBL7119866 | 0.74 | CNR2 (0.81) | CNR2CNR1ACHEBCHEMAPT | |
| SCHEMBL6971235 | 0.74 | CNR2 (0.47) | CNR2CNR1ACHEBCHEMGLL | |
| SCHEMBL6979571 | 0.74 | CNR2 (0.56) | CNR2CNR1ACHEMGLLABHD6 | |
| SCHEMBL7805412 | 0.74 | CNR2 (0.57) | CNR2CNR1ACHEMGLLABHD6 | |
| SCHEMBL5431708 | 0.73 | CNR2 (0.56) | CNR2CNR1ACHEMAPT | |
| SCHEMBL6969154 | 0.73 | CNR2 (0.54) | CNR2CNR1ACHEBCHEMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| CN-1305462-A | 1,5 and 3-O-substituted 1H-indazoles with antiasthmatic, antiallergic, antiinflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | DRESDEN ARZNEIMITTEL (DE) | 2001-07-25 | — | — | CN | claimed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |
| CN-1305462-A | 1,5 and 3-O-substituted 1H-indazoles with antiasthmatic, antiallergic, antiinflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | DRESDEN ARZNEIMITTEL (DE) | 2001-07-25 | — | — | CN | disclosed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | disclosed |