Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.52 |
| ▸ | ACHE | P22303 | 7/20 | 0.52 |
| ▸ | CNR1 | P21554 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973326 | 0.88 | CNR2 (0.58) | CNR2ACHECNR1MAPTSMN1; SMN2 | |
| SCHEMBL6978209 | 0.86 | CNR1 (0.49) | CNR2ACHECNR1MAPTKMT2A | |
| SCHEMBL6974448 | 0.85 | CNR1 (0.48) | CNR2ACHECNR1KMT2AKDM4E | |
| SCHEMBL6979571 | 0.83 | CNR2 (0.56) | CNR2ACHECNR1MAPTSMN1; SMN2 | |
| SCHEMBL6970142 | 0.83 | CNR2 (0.54) | CNR2ACHECNR1MAPTPIK3R1 | |
| SCHEMBL6975193 | 0.80 | CNR2 (0.51) | CNR2ACHECNR1MAPTPIK3R1 | |
| SCHEMBL8809942 | 0.79 | KDM4E (0.58) | CNR2ACHECNR1KDM4E | |
| SCHEMBL6970939 | 0.79 | CNR2 (0.47) | CNR2ACHECNR1MAPTPIK3R1 | |
| SCHEMBL6969154 | 0.78 | CNR2 (0.54) | CNR2ACHECNR1MAPTSMN1; SMN2 | |
| SCHEMBL6971235 | 0.78 | CNR2 (0.47) | CNR2ACHECNR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | claimed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | claimed |
| EP-1077947-B1 | NOVEL 1,5 AND 3-O-SUBSTITUTED 1H-INDAZOLES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY, IMMUNO-MODULATING AND NEURO-PROTECTIVE EFFECT, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | DRESDEN ARZNEIMITTEL (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-6166023-A | 1,5- and 3-O-substituted 1H-indazoles having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 2000-12-26 | — | — | US | disclosed |