SCHEMBL6965145

SCHEMBL6965145

O=C(O)c1ccccc1C(=O)C=Cc1ccc(OCc2ccc3ccccc3n2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CYSLTR2 Q9NS75 19/20 1.00
▸ CYSLTR1 Q9Y271 19/20 1.00
▸ GPBAR1 Q8TDU6 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965141 1.00 CYSLTR2 (1.00) CYSLTR2CYSLTR1GPBAR1
SCHEMBL30383176 1.00 CYSLTR2 (1.00) CYSLTR2CYSLTR1GPBAR1
SCHEMBL6177533 0.92 CYSLTR1 (1.00) CYSLTR2CYSLTR1
SCHEMBL6177529 0.92 CYSLTR1 (1.00) CYSLTR2CYSLTR1
SCHEMBL6965832 0.89 CYSLTR1 (1.00) CYSLTR2CYSLTR1GPBAR1
SCHEMBL6965825 0.89 CYSLTR1 (1.00) CYSLTR2CYSLTR1GPBAR1
SCHEMBL30382705 0.89 CYSLTR1 (1.00) CYSLTR2CYSLTR1GPBAR1
SCHEMBL8192801 0.88 CYSLTR1 (0.78) CYSLTR2CYSLTR1GPBAR1
SCHEMBL6969967 0.86 CYSLTR1 (1.00) CYSLTR2CYSLTR1
SCHEMBL6962892 0.86 CYSLTR1 (1.00) CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 — — US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 — — US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 — — US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
EP-0902007-B1 CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME KOWA CO (JP) 2003-11-05 — — EP disclosed
EP-0902007-A1 CHALCONE DERIVATIVES AND DRUGS CONTAINING THE SAME KOWA CO. LTD. (JP) 1999-03-17 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B CYSLTR2 3789/4885CYSLTR1 3956/4885GPBAR1 4425/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 CYSLTR2 2710/4885CYSLTR1 2263/4885GPBAR1 4291/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 CYSLTR2 2710/4885CYSLTR1 2263/4885GPBAR1 4291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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