Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951326 | 0.88 | ALDH1A1 (0.74) | ALDH1A1ALOX12RAB9AKDM4EPOLB | |
| SCHEMBL6957793 | 0.80 | ALDH1A1 (0.76) | ALDH1A1ALOX12RAB9AKDM4EPOLB | |
| SCHEMBL6952754 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALOX12RAB9AKDM4EPOLB | |
| SCHEMBL29352156 | 0.79 | ALDH1A1 (1.00) | ALDH1A1ALOX12RAB9AKDM4EPOLB | |
| SCHEMBL6957683 | 0.79 | ALDH1A1 (0.65) | ALDH1A1ALOX12RAB9AKDM4EPOLB | |
| SCHEMBL7082827 | 0.78 | ALDH1A1 (0.72) | ALDH1A1ALOX12RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL11839412 | 0.77 | ALDH1A1 (0.70) | ALDH1A1ALOX12RAB9AKDM4EPOLB | |
| Trovirdine SCHEMBL636095 | 0.77 | ALDH1A1 (0.71) | ALDH1A1ALOX12RAB9AKDM4ESMN1; SMN2 | |
| Trovirdine SCHEMBL2231102 | 0.76 | ALDH1A1 (0.70) | ALDH1A1ALOX12RAB9AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11837771 | 0.76 | ALDH1A1 (0.68) | ALDH1A1ALOX12RAB9AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540143-B1 | Compounds and methods for inhibition of HIV and related viruses | MEDIVIR AB (SE) | 2003-02-05 | — | — | EP | disclosed |
| US-5658907-A | THIOUREA VIRICIDES | MEDIVIR A/B (SE) | 1997-08-19 | — | — | US | disclosed |
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |
| EP-0540143-A2 | Compounds and methods for inhibition of HIV and related viruses | Medivir Aktiebolag (SE) | 1993-05-05 | — | — | EP | disclosed |