Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826872 | 0.81 | TDP1 (0.56) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL5573827 | 0.77 | TDP1 (0.43) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL35637 | 0.75 | TDP1 (0.46) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL8191946 | 0.75 | TDP1 (0.46) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL6965382 | 0.73 | TDP1 (0.44) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL10606468 | 0.73 | TDP1 (0.44) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL1668626 | 0.73 | TDP1 (0.44) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL21060526 | 0.73 | TDP1 (0.44) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| Sulfotep SCHEMBL22721240 | 0.73 | TSHR (0.45) | TDP1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL10790063 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |