Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7078897 | 0.89 | TP53 (0.38) | ALDH1A1HPGD | |
| SCHEMBL7080639 | 0.86 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL6973011 | 0.85 | MEN1 (0.34) | ALDH1A1HPGD | |
| SCHEMBL7087407 | 0.85 | RECQL (0.30) | — | |
| SCHEMBL6960619 | 0.84 | MEN1 (0.37) | ALDH1A1HPGD | |
| SCHEMBL8800652 | 0.82 | NPC1 (0.32) | NPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL6974554 | 0.82 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL7083284 | 0.82 | KDM4E (0.34) | ALDH1A1HPGD | |
| SCHEMBL6973187 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6968155 | 0.81 | TLR8 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |