SCHEMBL6965405

SCHEMBL6965405

CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)ccc2c1OC(C(=O)NCC(CCC)C(=O)O)CC2

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 0.76
LTB4R2 Q9NPC1 12/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6756167 0.95 LTB4R (0.73) LTB4RLTB4R2
SCHEMBL6756217 0.91 LTB4R (0.67) LTB4RLTB4R2
SCHEMBL7109811 0.90 LTB4R (0.65) LTB4RLTB4R2
SCHEMBL6756166 0.90 LTB4R (0.74) LTB4RLTB4R2
SCHEMBL6759809 0.88 LTB4R (0.74) LTB4RLTB4R2
SCHEMBL6968006 0.88 LTB4R (0.80) LTB4RLTB4R2
SCHEMBL6923414 0.87 LTB4R (0.72) LTB4RLTB4R2
SCHEMBL3679470 0.86 LTB4R (1.00) LTB4RLTB4R2
SCHEMBL6759556 0.86 LTB4R (0.75) LTB4RLTB4R2
SCHEMBL6756216 0.85 LTB4R (0.67) LTB4RLTB4R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999856-B1 RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION BRISTOL MYERS SQUIBB PHARMA CO (US) 2003-05-14 EP claimed