Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.54 |
| ▸ | CTSL | P07711 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375313 | 0.87 | CTSS (0.43) | CTSSCTSL | |
| SCHEMBL5367971 | 0.85 | CTSS (0.42) | CTSSCTSL | |
| SCHEMBL5364168 | 0.85 | CTSS (0.48) | CTSSCTSLOPRM1OPRL1 | |
| SCHEMBL5357225 | 0.85 | CTSS (0.48) | CTSSCTSLOPRM1OPRL1 | |
| SCHEMBL5362011 | 0.84 | CTSS (0.49) | CTSSCTSL | |
| SCHEMBL5357983 | 0.84 | CTSS (0.47) | CTSSCTSLOPRM1 | |
| SCHEMBL5362069 | 0.84 | CTSS (0.41) | CTSSCTSL | |
| SCHEMBL5361127 | 0.83 | CTSS (0.48) | CTSSCTSL | |
| SCHEMBL6972941 | 0.83 | CTSS (0.59) | CTSSOPRM1SMN1; SMN2 | |
| SCHEMBL5356435 | 0.82 | CTSS (0.46) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | disclosed |